EGF Receptor Substrate 2 [DADE-pY-LIPQQG], 5-FAM labeled

EGF Receptor Substrate 2 is a 5-FAM-labeled phosphopeptide derived from the EGFR autophosphorylation site at Tyr992. This fluorescent substrate is optimized for protein tyrosine phosphatase assays, including PTP1B and Yersinia PTP. Dephosphorylation produces a measurable fluorescence change, enabling sensitive detection and quantitative monitoring of phosphatase activity. EGF Receptor Substrate 2 is widely used in enzyme kinetics, inhibitor screening, phosphatase assay development, and signal transduction research involving EGFR phosphorylation. It supports studies of tyrosine phosphatase regulation, growth factor signaling, cancer pathways, and phosphorylation-dependent cellular communication.

Product Name: EGF Receptor Substrate 2 [DADE-pY-LIPQQG], 5-FAM labeled

Sequence One Letter Code: 5-FAM-DADE-pY-LIPQQG

Sequence Three Letter Code: 5-FAM-Asp-Ala-Asp-Glu-pTyr-Leu-Ile-Pro-Gln-Gln-Gly-OH

Chemical Formula:C76H93N12O30P

Molecular Weight: 1686.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Source / Species: Mammal

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26