Product Name: Endothelin 1, human, HiLyte™ Fluor 488-labeled
Sequence One Letter Code: HiLyte™ Fluor 488-CSCSSLMDKECVYFCHLDIIW (Disulfide Bridge: 1-15 and 3-11)
Sequence Three Letter Code: Hilyte™ Fluor 488-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide Bridge: 1-15 and 3-11)
Molecular Weight: 2848.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C Protected from light
Source / Species: human
Conjugation: Conjugated
Conjugation Type: Fluorescent dyes
Code Nacres: NA.26
Application: HiLyte™ Fluor 488 Endothelin-1 is a fluorescently labeled form of human endothelin-1 designed for visualization, receptor binding, and signaling studies. Endothelin-1 is a potent vasoconstrictor produced by endothelial cells and plays a central role in cardiovascular regulation, vascular tone, and endothelial function. Upon binding to G protein-coupled endothelin receptors, ET-1 activates intracellular signaling pathways, including protein kinase C-mediated cascades. The HiLyte™ Fluor 488 label enables real-time analysis of receptor binding, internalization, localization, and signaling dynamics. This peptide is widely used in cardiovascular, vascular biology, and metabolic disease research.
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