Eps8-Derived Peptide 327 is a human leukocyte antigen HLA-A*2402-restricted epitope originating from Eps8, a protein involved in actin dynamics and EGFR signaling. This peptide interferes with Eps8–EGFR complex formation, leading to suppression of EGFR signaling and downstream oncogenic pathways. It has been shown to reduce cancer cell viability and alter gene expression associated with tumor progression. Eps8-Derived Peptide 327 is valuable for studies of EGFR-targeted cancer therapy, peptide-based immunological intervention, protein–protein interaction disruption, tumor signaling, and therapeutic strategies aimed at Eps8-driven cancer mechanisms.
Product Name: Eps8-derived peptide 327
Sequence One Letter Code: EFLDCFQKF
Sequence Three Letter Code: H-Glu-Phe-Leu-Asp-Cys-Phe-Gln-Lys-Phe-OH
Chemical Formula:C56H77N11O15S
Molecular Weight: 1175.53
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Unconjugated
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