ERKtide [ATGPLSPGPFGRR]

Product Name: ERKtide [ATGPLSPGPFGRR]

Sequence One Letter Code: ATGPLSPGPFGRR

Sequence Three Letter Code: H-Ala-Thr-Gly-Pro-Leu-Ser-Pro-Gly-Pro-Phe-Gly-Arg-Arg-OH

Chemical Formula:C58H93N19O16

Molecular Weight: 1312.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Conjugation: Unconjugated

Code Nacres: NA.26

Application: ERKtide is a synthetic peptide substrate optimized for extracellular signal-regulated kinase 2 activity assays. ERK2 is a central kinase in the MAPK signaling cascade and regulates cell proliferation, differentiation, survival, and cellular responses to mitogenic stimulation. ERKtide contains a consensus phosphorylation motif recognized by ERK kinases, enabling efficient enzymatic phosphorylation and quantitative kinase activity profiling. This peptide is widely used in signal transduction research, MAPK pathway studies, kinase inhibitor development, and investigations of ERK-driven mechanisms in cancer, inflammation, cellular growth, differentiation, and survival signaling.