CAT.NO: P200532
CAS No:259230-56-3
Purity:95%
Molar Mass:654.8
Chemical Formula:C32H50N10O5
Categories: Bioactive Peptides, Growth Hormone–Related Peptide, Hormone & Metabolic Peptides, Uncategorized
Product Name:GHRP 3 TFA Salt
Synonyms:BR2Y2LGA6L
CAS No:259230-56-3
Purity:95%
Molar Mass:654.8
Chemical Formula:C32H50N10O5
Storage:Store at -20 degrees Celsius
Sequence:XWPIR
Application:GHRP-3 TFA Salt is a synthetic growth hormone-releasing peptide (GHRP) that stimulates the secretion of growth hormone (GH) by interacting with the ghrelin receptor (GHS-R1a). It is part of the GHRP family, which includes other peptides known to enhance GH release, thereby promoting anabolic processes, muscle growth, and fat metabolism. GHRP-3 is commonly used in research focused on endocrinology, metabolism, and aging, as it mimics the physiological release of growth hormone. Its TFA (trifluoroacetate) salt form ensures stability and solubility, making it suitable for various experimental and clinical applications, including studies on growth disorders and GH-related therapies.
Current Research:
Growth Hormone-Releasing Peptide-3 (GHRP-3) is a synthetic hexapeptide that stimulates the secretion of growth hormone (GH) from the anterior pituitary gland. Its sequence is H-D-Ala-D-Trp-D-Pro-D-Ile-L-Arg-NH?. The trifluoroacetate (TFA) salt form enhances its stability and solubility, making it suitable for various experimental and clinical applications.
Mechanism of Action
GHRP-3 binds to the growth hormone secretagogue receptor (GHS-R) on pituitary somatotrophs, triggering a signaling cascade that leads to increased GH release. This action mimics the natural GH-releasing hormone (GHRH), promoting anabolic effects such as muscle growth and improved metabolism.
Applications
Research: GHRP-3 is utilized in studies investigating GH regulation, endocrine function, and metabolic processes.
Clinical Potential: Its ability to elevate GH levels suggests potential therapeutic applications in conditions like GH deficiency and muscle-wasting disorders.
Handling and Storage
GHRP-3 TFA salt should be stored in a refrigerator to maintain its stability. It is slightly soluble in methanol and water, facilitating its use in various formulations.
Safety Considerations
As with all research peptides, appropriate safety protocols should be followed to prevent unintended exposure.
Conclusion
GHRP-3 TFA salt is a valuable tool in endocrinological research and holds promise for therapeutic applications related to growth hormone modulation.
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