gp91 ds-tat Peptide 2

Product Name: gp91 ds-tat Peptide 2

Sequence One Letter Code: RKKRRQRRRCSTRIRRQL-NH2

Sequence Three Letter Code: H-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2

Chemical Formula:C98H190N50O22S1

Molecular Weight: 2453

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: HIV

Conjugation: Unconjugated

Code Nacres: NA.26

Application: gp91 ds-tat Peptide 2 is a cell-permeable peptide inhibitor designed to disrupt NADPH oxidase assembly and reduce reactive oxygen species generation. It contains a truncated gp91phox docking sequence linked to the HIV-tat transduction domain, enabling efficient uptake across diverse cell types. Compared with the original gp91 ds-tat peptide, this variant is two amino acid residues shorter at the N-terminus while retaining inhibitory activity. gp91 ds-tat Peptide 2 is widely used in studies of oxidative stress, redox signaling, inflammation, cardiovascular dysfunction, and metabolic disease mechanisms involving NADPH oxidase-dependent ROS production.