Human PD-L1 inhibitor IV

Product Name: Human PD-L1 inhibitor IV

Sequence One Letter Code: GNWDYNSQRAQLYNQ

Sequence Three Letter Code: H-Gly-Asn-Trp-Asp-Tyr-Asn-Ser-Gln-Arg-Ala-Gln-Leu-Tyr-Asn-Gln-OH

Chemical Formula:C80H113N25O27

Molecular Weight: 1857

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Human PD-L1 Inhibitor IV is a synthetic peptide that binds to the PD-1 receptor and disrupts the PD-1/PD-L1 immune checkpoint interaction. This pathway plays a central role in regulating T-cell activity, and many tumors exploit PD-L1 overexpression to suppress immune surveillance. The peptide contains key anchor residues, including the GNWDYNSQRAQLYNQ motif, which contribute strongly to PD-1 binding affinity. Human PD-L1 Inhibitor IV is widely used in immuno-oncology research to investigate immune checkpoint inhibition, T-cell activation, tumor immune escape, PD-1/PD-L1 signaling, and peptide-based therapeutic strategy development.