Human PD-L1 inhibitor II

Product Name: Human PD-L1 inhibitor II

Sequence One Letter Code: FNWDYSLEELREKAKYK

Sequence Three Letter Code: H-Phe-Asn-Trp-Asp-Tyr-Ser-Leu-Glu-Glu-Leu-Arg-Glu-Lys-Ala-Lys-Tyr-Lys-OH

Chemical Formula:C103H151N25O30

Molecular Weight: 2219.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Human PD-L1 Inhibitor II is a synthetic peptide that binds the PD-1 receptor and blocks PD-1/PD-L1 interaction, a key immune checkpoint pathway involved in T-cell suppression. Many cancer cells overexpress PD-L1 to evade immune surveillance, making this pathway an important focus in immuno-oncology research. This peptide contains key anchor residues, including the WDY motif, which contribute to PD-1 binding. Human PD-L1 Inhibitor II is widely used to study immune checkpoint regulation, T-cell activation, tumor immune escape, PD-1/PD-L1 blockade mechanisms, and screening or validation of checkpoint-targeted therapeutics.