GRGDTP

Product Name: GRGDTP

Sequence One Letter Code: GRGDTP

Sequence Three Letter Code: H-Gly-Arg-Gly-Asp-Thr-Pro-OH

Cas No: 108682-58-2

Chemical Formula:C23H39N9O10

Molecular Weight: 601.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: CC(C(C(=O)N1CCCC1C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)O

IUPAC: 1-[2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid

INCHIKEY: UMZVBZDHGKJFGQ-UHFFFAOYSA-N

INCHI:

InChI=1S/C23H39N9O10/c1-11(33)18(21(40)32-7-3-5-14(32)22(41)42)31-20(39)13(8-17(36)37)30-16(35)10-28-19(38)12(29-15(34)9-24)4-2-6-27-23(25)26/h11-14,18,33H,2-10,24H2,1H3,(H,28,38)(H,29,34)(H,30,35)(H,31,39)(H,36,37)(H,41,42)(H4,25,26,27)

Source / Species: synthetic

Conjugation: Unconjugated

Code Nacres: NA.26

Application: GRGDTP is a short integrin-binding peptide containing the classical Arg-Gly-Asp motif, a key recognition sequence that mediates cell adhesion to extracellular matrix proteins. RGD-containing peptides interact with multiple integrin receptors and are widely used to study cell attachment, migration, angiogenesis, and integrin-mediated signaling. GRGDTP is valuable in biomaterials research, tissue engineering, and integrin-targeted therapeutic development. It is commonly applied in competitive inhibition assays and surface functionalization strategies to modulate integrin-dependent cellular responses. This peptide supports studies of extracellular matrix interactions, adhesion biology, and cell–material interface design.