Human PD-L1 inhibitor III

Product Name: Human PD-L1 inhibitor III

Sequence One Letter Code: TEKDYRHGNIRMKLAYDL

Sequence Three Letter Code: H-Thr-Glu-Lys-Asp-Tyr-Arg-His-Gly-Asn-Ile-Arg-Met-Lys-Leu-Ala-Tyr-Asp-Leu-OH

Chemical Formula:C97H155N29O29S1

Molecular Weight: 2223.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Human PD-L1 Inhibitor III is a synthetic peptide that binds the PD-1 receptor and blocks PD-1/PD-L1 interaction, a central immune checkpoint pathway that suppresses T-cell activation. Many tumors exploit PD-L1 overexpression to evade immune surveillance, making this pathway a major focus in immuno-oncology research. This peptide contains key anchor residues within the TEKDYRHGNIRMKLAYDL sequence that strongly contribute to PD-1 binding. Human PD-L1 Inhibitor III is widely used to study immune checkpoint regulation, T-cell activation, tumor immune escape, PD-1/PD-L1 blockade mechanisms, and peptide-based checkpoint-targeting strategies.