Hyp3-Des-Arg9-Bradykinin

Product Name: Hyp3-Des-Arg9-Bradykinin

Sequence One Letter Code: RPOGFSPF

Sequence Three Letter Code: Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe

Molecular Weight: 920.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Conjugation: Unconjugated

Code Nacres: NA.29 Application: Hyp³-Des-Arg⁹-Bradykinin is a hydroxylated kinin peptide that acts as an agonist of the bradykinin B1 receptor. This peptide arises from kininogen cleavage by plasma kallikrein followed by hydroxylation of the proline residue at position 3. Like other B1 receptor agonists, Hyp³-Des-Arg⁹-Bradykinin is involved in inflammatory responses, vascular regulation, pain signaling, and pathological kinin receptor activation. It is valuable for studying post-translationally modified kinins, inducible bradykinin receptor signaling, inflammation-associated vascular permeability, pain mechanisms, and the biological significance of hydroxylated kinin metabolites in disease models.