KALA

Product Name: KALA

Sequence One Letter Code: WEAKLAKALAKALAKHLAKALAKALKACEA

Sequence Three Letter Code: Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala-OH

Cas No: 187987-64-0

Chemical Formula:C144H248N40O35S

Molecular Weight: 3132.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Synthetic construct

Conjugation: Unconjugated

Code Nacres: NA.26

Application: KALA is a cationic, amphipathic cell-penetrating peptide designed for intracellular delivery applications. At physiological pH, KALA adopts an α-helical conformation that supports strong interactions with nucleic acids and cellular membranes. This peptide can bind oligonucleotides and disrupt membrane integrity, facilitating cellular uptake of DNA and RNA cargoes. Because of these properties, KALA is frequently used as a non-viral transfection reagent and delivery tool. It is widely applied in gene delivery, nucleic acid therapeutics, intracellular transport, membrane interaction studies, and development of peptide-based delivery systems for molecular biology research.