[Lys(Ac)16]-Histone H4 (1-25)-GSGSK(Biotin)

Product Name: [Lys(Ac)16]-Histone H4 (1-25)-GSGSK(Biotin)

Sequence One Letter Code: SGRGKGGKGLGKGGA-K(Ac)-RHRKVLRDN-GSGSK(Biotin)

Sequence Three Letter Code: H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Leu-Arg-Asp-Asn-Gly-Ser-Gly-Ser-Lys(Biotin)-OH

Molecular Weight: 3274.9

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: Histone H4 (1–25), K16ac-Biotin is a synthetic histone H4 peptide monoacetylated at lysine 16, the most prevalent acetylation site on histone H4. H4K16 acetylation plays a critical role in chromatin decondensation, transcriptional regulation, and modification-dependent protein recruitment. Loss of this mark has been associated with human tumor cells and altered gene expression patterns. The peptide contains a C-terminal GSGSK linker followed by biotinylated lysine, enabling pull-down, binding, and interaction assays. It is widely used in epigenetics research to study acetylation-dependent chromatin remodeling and histone reader protein recognition.