[Lys(Me1)20]-Histone H4 (1–23)-GGK(Biotin) is a synthetic histone H4 peptide corresponding to residues 1–23 and monomethylated at lysine 20. H4K20 monomethylation is a conserved epigenetic modification associated with chromosomal memory, genome stability, DNA repair, and cell cycle regulation. This mark is dynamically regulated throughout the cell cycle and is especially abundant during S phase. The peptide includes a C-terminal GG linker and biotinylated lysine, enabling streptavidin-based capture, pull-down, and binding assays. It is widely used in chromatin biology and epigenetics research to study methyl-lysine recognition and H4K20-dependent protein recruitment.
Product Name: [Lys(Me1)20]-Histone H4 (1-23)-GGK(Biotin)-NH2
Sequence One Letter Code: SGRGKGGKGLGKGGAKRHR-K(Me1)-VLR-GGK(Biotin)-NH2
Sequence Three Letter Code: H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys(Me1)-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-NH2
Molecular Weight: 2842.6
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Conjugated
Conjugation Type: Biotins
Code Nacres: NA.26
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