[Lys(Me2)4]-Histone H3 (1-10)

Product Name: [Lys(Me2)4]-Histone H3 (1-10)

Sequence One Letter Code: ART-K(Me2)-QTARKS

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys(Me2)-Gln-Thr-Ala-Arg-Lys-Ser-OH

Molecular Weight: 1174.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: [Lys(Me2)4]-Histone H3 (1–10) is a synthetic histone H3 peptide corresponding to residues 1–10 and dimethylated at lysine 4. H3K4 dimethylation is associated with transcriptionally permissive chromatin states and is frequently found near promoters and enhancers. This mark serves as an intermediate between mono- and trimethylated H3K4 states, making it useful for studying histone methylation dynamics. [Lys(Me2)4]-Histone H3 (1–10) is widely used in epigenetics and chromatin biology research to investigate methyltransferase specificity, demethylase activity, methyl-lysine reader interactions, promoter regulation, and enhancer-associated chromatin signaling.