[Lys(Me3)20]-Histone H4 (1-23)-GGK(Biotin)-NH2

Product Name: [Lys(Me3)20]-Histone H4 (1-23)-GGK(Biotin)-NH2

Sequence One Letter Code: SGRGKGGKGLGKGGAKRHR-K(Me3)-VLR-GGK(Biotin)-NH2

Sequence Three Letter Code: H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys(Me3)-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-NH2

Molecular Weight: 2871.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me3)20]-Histone H4 (1–23)-GGK(Biotin) is a synthetic histone H4 peptide trimethylated at lysine 20, a key epigenetic modification linked to heterochromatin formation, transcriptional repression, genome integrity, and DNA damage repair. The peptide represents the N-terminal residues 1–23 of histone H4 and includes a C-terminal GG linker plus biotinylated lysine for pull-down and binding assays. [Lys(Me3)20]-Histone H4 is widely used to investigate chromatin compaction, H4K20me3-recognizing effector proteins, histone modification crosstalk, repressive chromatin states, and methylation-dependent chromatin regulation.