Product Name: Myristoyl-Octapeptide-2
Purity: 95%
Storage: Keep in dark and cool dry place -5~8 degree Celsius
Sequence: Myr-KLKKTETQ-NH2
Molar Mass: 1185.52
Chemical Formula: C56H104N12O15
Synonyms: Myristoyl-KLKKTETQ, tetradecanoyl-L-lysyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-glutamyl-L-threonyl-L-glutamine
Application:
Myristoyl-Octapeptide-2 is a lipidated peptide designed to enhance delivery and activity within the skin and scalp. By coupling an octapeptide sequence with a myristoyl group, this ingredient supports studies on strengthening hair follicles, improving scalp vitality, and promoting the appearance of fuller, healthier-looking hair. In skincare applications, it is valued for its potential to support firmness and resilience by encouraging optimal cellular communication. Its increased stability and affinity for lipid-rich environments make it ideal for serums, leave-on treatments, and advanced hair-care formulas focused on revitalization, density improvement, and overall structural support.
Current Research:
Myristoyl-Octapeptide-2: Current Research & Cosmetic Positioning
Myristoyl-Octapeptide-2 is a myristoylated bioactive peptide positioned primarily for hair growth support, lash/brow enhancement, and anti-aging skin care. It is the lipid-modified version of Octapeptide-2, a small peptide originally studied for wound healing and hair-growth promotion when applied topically. In cosmetics, attaching a myristoyl (C14) fatty acid to the N-terminus improves skin affinity and stability, making the peptide more suitable for real-world formulas.
Octapeptide-2 is described as a synthetic growth-factor–like peptide composed of amino acids such as glutamic acid, glutamine, leucine, lysine and threonine, arranged in a short motif (commonly referenced as LKKTETQ or closely related sequences). This sequence has been investigated as a topical agent that can:
Support wound healing in experimental models
Promote hair growth by influencing signaling in hair follicles
Myristoyl-Octapeptide-2 is simply this octapeptide with a myristoyl group attached. The lipid tail increases its lipophilicity, helping it partition into the stratum corneum and around follicular openings, where it can better interact with keratinocytes and follicle cells. Cosmetic suppliers typically classify it as a hair/eyelash/eyebrow care peptide and as an anti-wrinkle peptide that also supports hydration and softness.
A key application area for Myristoyl-Octapeptide-2 is hair and scalp care:
Octapeptide-2 has been reported to promote hair growth in animal models, where topical application activated existing follicles and improved hair coverage.
Mechanistically, it is often described as acting partly by counteracting inhibitory signals (such as BMP4) in hair follicle development, supporting a more growth-favorable environment at the cosmetic level.
Myristoylation enhances its residence time on the scalp and near follicles, which is why this derivative appears in scalp serums, anti-thinning shampoos, and hair-density treatments.
In ingredient catalogues, Myristoyl-Octapeptide-2 is frequently grouped with other hair-generating and lash-enhancing peptides (such as myristoyl pentapeptides and biotinoyl tripeptides). This positions it strongly for:
Fuller-looking hair and improved appearance of density
Thicker, more resilient-looking eyelashes and eyebrows
“Strengthening” and “re-energizing” scalp concepts in leave-on formulations
Beyond hair, Myristoyl-Octapeptide-2 is also marketed as an anti-wrinkle and skin-conditioning peptide:
Supplier data highlight improvements in skin wrinkles, hydration, and softness when it is incorporated into face and eye products.
By supporting keratinocyte activity and surface renewal, it helps refine skin texture and contributes to a smoother, more supple appearance.
As a peptide with growth-factor–like behavior, it fits well into “skin revitalization” and “regeneration-inspired” stories at the cosmetic level.
The myristoyl group gives the molecule a mild film-forming and conditioning character, which can enhance the sensorial feel of creams and serums and improve perceived plumpness and comfort.
Although detailed human clinical data are still relatively limited, several mechanistic themes stand out in the literature and technical dossiers:
Hair-follicle support: Octapeptide-2 is associated with stimulation of follicular activity and promotion of growth-phase hair, which translates into visible density benefits in cosmetic use.
Wound healing and repair: Experimental work has shown activity in full-thickness dermal wound models, suggesting a capacity to support cell migration and tissue repair. This underpins its positioning for recovery, resilience, and renewal in skin care.
Surface conditioning: The combination of a peptide core and fatty acid tail provides both biological signaling and conditioning/softening effects on the skin and hair shaft.
These mechanisms make Myristoyl-Octapeptide-2 a good match for “rebuild, renew, strengthen” narratives across both hair and skin categories.
From a formulator’s viewpoint, Myristoyl-Octapeptide-2 is typically supplied as a white, lyophilized powder with high purity, intended for dissolution into the water phase or suitable solvents:
Used at low active levels in serums, gels, emulsions, shampoos, and lash/brow serums.
Often added in the cool-down phase to preserve peptide integrity.
Compatible with other hair/skin actives such as caffeine, niacinamide, panthenol, plant extracts, and additional peptides (for example, lash/brow complexes or scalp-care blends).
You can confidently present Myristoyl-Octapeptide-2 as:
A growth-factor–inspired myristoylated peptide that supports hair growth and follicle vitality at the cosmetic level.
A multifunctional active for hair, lash, and brow products aiming at fuller, stronger, more resilient-looking fibers.
A skin-conditioning and anti-wrinkle peptide that helps improve the look of fine lines while enhancing hydration and softness.
That makes it ideal for hair-density serums, anti-thinning systems, lash/brow boosters, and advanced anti-aging formulations in a high-performance, peptide-focused cosmetic line.
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