NRC-16

Product Name: NRC-16

Sequence One Letter Code: GWKKWLRKGAKHLGQAAIK

Sequence Three Letter Code: H-Gly-Trp-Lys-Lys-Trp-Leu-Arg-Lys-Gly-Ala-Lys-His-Leu-Gly-Gln-Ala-Ala-Ile-Lys-OH

Chemical Formula:C102H166N32O21

Molecular Weight: 2176.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Flatfish; flounder

Conjugation: Unconjugated

Code Nacres: NA.26

Application: NRC-16 is a 19-amino-acid cationic antimicrobial peptide originally derived from witch flounder. It demonstrates broad-spectrum inhibitory activity against Gram-negative bacteria, Gram-positive bacteria, and fungal pathogens. NRC-16 has also shown strong antibiofilm effects, including prevention of biofilm formation in Pseudomonas aeruginosa strains without inducing cytotoxicity. Its combination of antimicrobial potency, antibiofilm activity, and low host toxicity makes NRC-16 a valuable peptide for infection biology research. It is widely used to study host defense peptides, biofilm-associated infections, microbial inhibition, and new therapeutic strategies against resistant pathogens.