OVA-Q4 Peptide, pQ4, SIIQFEKL, OVA (257-264) Variant

OVA-Q4 (SIIQFEKL) is an altered peptide ligand derived from the immunodominant ovalbumin epitope SIINFEKL and presented by murine H-2Kᵇ MHC class I molecules. The substitution at position 4 modifies T-cell receptor signaling properties while maintaining MHC binding affinity. OVA-Q4 is widely used to probe T-cell sensitivity, antigen discrimination, signaling thresholds, effector differentiation, and tolerance mechanisms. This peptide is valuable in immunology research focused on altered peptide ligands, CD8⁺ T-cell activation, immune modulation, T-cell receptor recognition, and functional regulation of antigen-specific cellular immune responses.

Product Name: OVA-Q4 Peptide, pQ4, SIIQFEKL, OVA (257-264) Variant

Sequence One Letter Code: SIIQFEKL

Sequence Three Letter Code: H-Ser-Ile-Ile-Gln-Phe-Glu-Lys-Leu-OH

Chemical Formula:C46H76N10O13

Molecular Weight: 977.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: chicken

Conjugation: Unconjugated

Code Nacres: NA.26