PKC β pseudosubstrate

Product Name:PKC β pseudosubstrate

CAS No:172308-76-8

Purity:95%

Molar Mass:3995

Chemical Formula:C177H294N62O38S3

Storage:Store at -20 degrees Celsius

Sequence:CRQIKIWFQNRRMKWKK CRFARKGALRQKNV

Target:cell-permeable peptide inhibitor of protein kinase

Application:PKC β Pseudosubstrate is a synthetic peptide designed to inhibit the activity of Protein Kinase C beta (PKC β) by mimicking its autoinhibitory domain. This peptide specifically binds to the active site of PKC β, preventing its activation and downstream signaling. PKC β Pseudosubstrate is a valuable tool for researchers investigating the role of PKC β in various cellular processes, such as signal transduction, cell proliferation, and apoptosis. With its high specificity and purity, this peptide ensures precise and reproducible results, making it essential for studies targeting PKC β-related pathways in both physiological and pathological contexts.

Reference:

Walser, R., Burke, J. E., Gogvadze, E., Bohnacker, T., Zhang, X., Hess, D., ... & Wymann, M. P. (2013). PKC?? phosphorylates PI3K?? to activate it and release it from GPCR control. PLoS biology, 11(6), e1001587.