Product Name: PKCd (8-17), PKCd Inhibitor
Sequence One Letter Code: SFNSYELGSL
Sequence Three Letter Code: H-Ser-Phe-Asn-Ser-Tyr-Glu-Leu-Gly-Ser-Leu-OH
Chemical Formula:C50H73N11O18
Molecular Weight: 1116.2
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: mouse, rat
Conjugation: Unconjugated
Code Nacres: NA.26
Application: PKCδ V1 Domain Inhibitory Peptide is derived from the V1 domain of protein kinase C delta and selectively inhibits PKCδ translocation and activation induced by phorbol esters such as PMA. By blocking PKCδ signaling, this peptide modulates pathways involved in cell survival, proliferation, stress responses, and tissue injury. PKCδ inhibition has been reported to reduce ischemic injury in cardiac and cerebral tissues, promote fibroblast proliferation, and suppress graft coronary artery disease in experimental models. This peptide is widely used in cardiovascular, neurological, signal transduction, ischemia, and kinase pathway research.
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