PSTi8

Product Name: PSTi8

Sequence One Letter Code: PEGKGEQEHSQQKEEEEEMAV-NH2

Sequence Three Letter Code: Pro-Glu-Gly-Lys-Gly-Glu-Gln-Glu-His-Ser-Gln-Gln-Lys-Glu-Glu-Glu-Glu-Glu-Met-Ala-Val-NH2

Chemical Formula:C138H216N40O51S1

Molecular Weight: 2426.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Application: PSTi8 is a biologically active short variant of pancreastatin generated by proteolytic processing of chromogranin A. Corresponding to residues 24–44, PSTi8 regulates glucose and energy metabolism by inhibiting glycogen synthesis and modulating glucose-stimulated insulin secretion. It also influences lipid and protein metabolism in adipose tissue and liver. PSTi8 has demonstrated potent antidiabetic activity in animal models, making it valuable for metabolic disease research. This peptide is widely used to study insulin resistance, glucose regulation, pancreastatin signaling, type 2 diabetes mechanisms, and endocrine control of energy metabolism.