520 MMP FRET Substrate 13

Product Name: 520 MMP FRET Substrate 13

Sequence One Letter Code: 5-FAM-RPKPVE-Nva-WRK(QXL® 520)-NH2

Sequence Three Letter Code: 5-FAM-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(QXL® 520)-NH2

Molecular Weight: 2144.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Conjugation: Conjugated

Conjugation Type: Double dyes

Code Nacres: NA.26

Application: MMP-3/MMP-12 Fluorogenic Substrate is a synthetic peptide substrate designed for sensitive detection of matrix metalloproteinase activity, particularly MMP-3 and MMP-12. Matrix metalloproteinases are important endopeptidases involved in extracellular matrix remodeling, cytokine regulation, angiogenesis, cell migration, and inflammatory responses. Upon enzymatic cleavage, the substrate generates fluorescence measurable at Abs/Em 494/521 nm, enabling quantitative protease activity assays. This fluorogenic MMP substrate is widely used in studies of tissue remodeling, cancer progression, inflammation, protease kinetics, and inhibitor screening targeting MMP-driven pathways.