Angiotensin (1-7)

Product Name: Angiotensin (1-7)

Sequence One Letter Code: DRVYIHP

Sequence Three Letter Code: H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH

Cas No: 51833-78-4

Chemical Formula:C41H62N12O11

Molecular Weight: 899.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N

IUPAC: (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid

INCHIKEY: PVHLMTREZMEJCG-GDTLVBQBSA-N

INCHI:

InChI=1S/C41H62N12O11/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56/h10-13,19-22,26-30,32-33,54H,5-9,14-18,42H2,1-4H3,(H,45,47)(H,48,57)(H,49,60)(H,50,61)(H,51,58)(H,52,59)(H,55,56)(H,63,64)(H4,43,44,46)/t22-,26-,27-,28-,29-,30-,32-,33-/m0/s1

Source / Species: mouse

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Angiotensin (1–7) is a bioactive heptapeptide generated from angiotensin I or angiotensin II through alternative enzymatic processing. Unlike angiotensin II, Angiotensin (1–7) exerts vasodilatory, natriuretic, anti-inflammatory, and antiproliferative effects. These actions are mediated primarily through the G protein-coupled Mas receptor. Angiotensin (1–7) is widely used in cardiovascular, renal, and metabolic research to study counter-regulatory pathways within the renin–angiotensin system. It supports investigations of blood pressure control, vascular protection, tissue repair, renal function, endothelial signaling, and therapeutic strategies targeting protective RAS signaling.