[Arg8]-Vasopressin (AVP) Peptide

Product Name: [Arg8]-Vasopressin (AVP) Peptide

Sequence One Letter Code: CYFQNCPRG-NH2 (Disulfide bridge: 1-6)

Sequence Three Letter Code: H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-6)

Cas No: 113-79-1

Chemical Formula:C46H65N15O12S2

Molecular Weight: 1084.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N

IUPAC: (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

INCHIKEY: KBZOIRJILGZLEJ-LGYYRGKSSA-N

INCHI:

InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1

Source / Species: human, bovine, mouse, rat

Conjugation: Unconjugated

Code Nacres: NA.26

Application: [Arg8]-Vasopressin, also known as arginine vasopressin or AVP, is a nonapeptide hormone essential for fluid balance, electrolyte regulation, and cardiovascular homeostasis. It exerts antidiuretic effects in the kidney by promoting water reabsorption through vasopressin receptor signaling. Beyond renal function, arginine vasopressin also influences vascular tone, blood pressure regulation, and cardiovascular responses under physiological and stress conditions. Circulating AVP levels increase during dehydration and myocardial infarction, supporting hemodynamic stabilization. This peptide is widely used in endocrine research, renal physiology studies, cardiovascular biology, and vasopressin receptor signaling investigations.