Bak BH3 (72-87)

Product Name: Bak BH3 (72-87)

Sequence One Letter Code: GQVGRQLAIIGDDINR

Sequence Three Letter Code: H-Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-OH

Chemical Formula:C72H125N25O24

Molecular Weight: 1725.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Bak BH3 (72–87) is a synthetic peptide derived from the BH3 domain of Bak, a pro-apoptotic Bcl-2 family protein involved in mitochondrial cell death signaling. This sequence, also known as Flu-BakBH3, binds with high affinity to a critical surface pocket of the anti-apoptotic protein Bcl-XL, which is essential for its death-antagonist function. Bak BH3 (72–87) is widely used in apoptosis research, cancer biology, and studies of Bcl-2 family protein interactions. It supports investigations of mitochondrial membrane permeabilization, apoptotic resistance, and therapeutic strategies targeting cancer cell survival pathways.