Product Name: Beta-Amyloid (20-42)
Sequence One Letter Code: FAEDVGSNKGAIIGLMVGGVVIA
Sequence Three Letter Code: H-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Chemical Formula:C99H165N25O30S
Molecular Weight: 2217.8
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Unconjugated
Code Nacres: NA.26
Application: Beta-Amyloid (20–42) is a synthetic peptide fragment corresponding to the hydrophobic C-terminal region of amyloid-β. This region plays a critical role in peptide aggregation, fibril formation, membrane interaction, and cytotoxicity. Due to its strong aggregation propensity, Aβ(20–42) is commonly used as a model system for investigating structural determinants of amyloid assembly and fibrillogenesis. Beta-Amyloid (20–42) supports biophysical studies, aggregation inhibitor screening, membrane interaction assays, and mechanistic research into Alzheimer’s disease amyloid pathology. It is valuable for exploring how C-terminal amyloid sequences drive neurotoxic peptide assembly.
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