Product Name: Dipeptidylaminopeptidase IV Substrate, fluorescent H-Gly-Pro-AMC
Sequence One Letter Code: GP-AMC
Sequence Three Letter Code: H-Gly-Pro-AMC
Chemical Formula:C17H19N3O4
Molecular Weight: 329.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C Protected from light
Source / Species: Synthetic construct
Conjugation: Conjugated
Conjugation Type: Fluorescent dyes
Code Nacres: NA.26
Application: H-Gly-Pro-AMC is a fluorogenic peptide substrate for dipeptidyl peptidase IV, also known as DPP-IV or CD26. DPP-IV plays an important role in metabolic regulation by degrading incretin hormones such as GLP-1 and also contributes to immune signaling. Upon enzymatic cleavage, this substrate releases the AMC fluorophore, producing fluorescence detectable at Abs/Em 353/442 nm. H-Gly-Pro-AMC is widely used in DPP-IV activity assays, enzyme kinetics, inhibitor screening, diabetes research, metabolic disease studies, and biochemical investigations of DPP-IV function, hormone degradation, and therapeutic target validation.
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