Product Name: Proteases Substrate, Fluorogenic, (Z-R)2Rh110•2HCl
Sequence One Letter Code: (Z-R)2Rh110•2HCl
Sequence Three Letter Code: (Z-Arg)2Rh110 • 2HCl
Molecular Weight: 914.0•73.0
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: -20°C Protected from Light
Source / Species: Synthetic construct
Conjugation: Conjugated
Conjugation Type: Fluorescent dyes
Code Nacres: NA.26
Application: (Z-Arg)₂Rh110 is a generic fluorogenic substrate for broad protease detection, including trypsin, cathepsin B, and cathepsin L. Upon enzymatic hydrolysis, the non-fluorescent precursor releases highly fluorescent rhodamine 110, generating strong signal intensity compatible with standard fluorescence instruments. With excitation and emission wavelengths of 501/527 nm, this substrate enables sensitive monitoring of protease kinetics, enzyme activity, and inhibitor performance. (Z-Arg)₂Rh110 is widely used in protease research, lysosomal enzyme studies, biochemical assay development, drug discovery workflows, and screening applications targeting proteolytic pathways.
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