Gastrin-1, human (Leu15)

Product Name: Gastrin-1, human (Leu15)

Sequence One Letter Code: Pyr-GPWLEEEEEAYGWLDF-NH2

Sequence Three Letter Code: Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

Cas No: 39024-57-2

Chemical Formula:C98H126N20O31

Molecular Weight: 2080.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NCC(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC4=CC=CC=C4)C(=O)N)NC(=O)C(CC5CNC6=CC=CC=C56)NC(=O)C7CCCN7C(=O)CNC(=O)C8CCC(=O)N8

IUPAC: 5-[[1-[[1-[[2-[[1-[[1-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-[[4-carboxy-2-[[4-carboxy-2-[[4-carboxy-2-[[4-carboxy-2-[[2-[[3-(2,3-dihydro-1H-indol-3-yl)-2-[[1-[2-[(5-oxopyrrolidine-2-carbonyl)amino]acetyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]-5-oxopentanoic acid

INCHIKEY: LNMSYFTWEWHYHX-UHFFFAOYSA-N

INCHI:

InChI=1S/C98H128N20O31/c1-49(2)38-68(115-96(147)72(43-55-46-101-60-19-12-10-17-58(55)60)117-98(149)74-20-13-37-118(74)77(122)48-103-86(137)61-25-31-75(120)105-61)93(144)111-66(30-36-82(131)132)92(143)110-65(29-35-81(129)130)91(142)109-64(28-34-80(127)128)90(141)108-63(27-33-79(125)126)89(140)107-62(26-32-78(123)124)88(139)104-51(5)85(136)113-70(41-53-21-23-56(119)24-22-53)87(138)102-47-76(121)106-71(42-54-45-100-59-18-11-9-16-57(54)59)95(146)114-69(39-50(3)4)94(145)116-73(44-83(133)134)97(148)112-67(84(99)135)40-52-14-7-6-8-15-52/h6-12,14-19,21-24,45,49-51,55,61-74,100-101,119H,13,20,25-44,46-48H2,1-5H3,(H2,99,135)(H,102,138)(H,103,137)(H,104,139)(H,105,120)(H,106,121)(H,107,140)(H,108,141)(H,109,142)(H,110,143)(H,111,144)(H,112,148)(H,113,136)(H,114,146)(H,115,147)(H,116,145)(H,117,149)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H,131,132)(H,133,134)

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Stabilized Human Gastrin-1 Analog is a synthetic peptide in which leucine replaces the native residue at position 15 to enhance peptide stability while retaining biological activity. Gastrin-1 is a gastrointestinal hormone that stimulates gastric acid secretion and regulates gastrointestinal growth, motility, and endocrine signaling. This stabilized analog provides a reliable tool for investigating gastrin receptor activation, hormone–receptor interactions, and downstream signaling pathways involved in digestive system regulation. It is widely used in gastric physiology research, gastrointestinal disease models, peptide hormone studies, CCK2/gastrin receptor pharmacology, and digestive endocrine signaling analysis.