gp100 (25-33), mouse

Product Name: gp100 (25-33), mouse

Sequence One Letter Code: EGSRNQDWL

Sequence Three Letter Code: H-Glu-Gly-Ser-Arg-Asn-Gln-Asp-Trp-Leu-OH

Chemical Formula:C46H69N15O17

Molecular Weight: 1104.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: mouse

Conjugation: Unconjugated

Code Nacres: NA.26

Application: gp100 (25–33) is a synthetic peptide corresponding to residues 25–33 of mouse glycoprotein gp100, a melanocyte differentiation antigen involved in pigment synthesis. This peptide represents an H-2Dᵇ-restricted CD8⁺ T-cell epitope recognized by cytotoxic T lymphocytes. Because gp100 is expressed in normal melanocytes and melanoma cells, gp100 (25–33) is widely used as a model antigen in tumor immunology. It supports studies of antigen-specific T-cell responses, melanoma immunotherapy, immune tolerance, tumor-associated antigen recognition, cytotoxic immune activation, and vaccine strategies targeting melanoma-associated epitopes.