gp91 ds-tat, FAM labeled

Product Name: gp91 ds-tat, FAM labeled

Sequence One Letter Code: 5-FAM-YGRKKRRQRRRCSTRIRRQL-NH2

Sequence Three Letter Code: 5-FAM-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2

Chemical Formula:C130H212N52O31S1

Molecular Weight: 3031.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Source / Species: HIV

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26

Application: gp91 ds-tat, FAM labeled, is a fluorescent cell-permeable peptide inhibitor of NADPH oxidase assembly. It combines a gp91phox-derived inhibitory sequence with the HIV-tat cell-penetrating peptide for efficient intracellular delivery and a fluorescein label for visualization and tracking. This design enables simultaneous inhibition of NADPH oxidase-mediated reactive oxygen species production and monitoring of peptide localization inside cells. gp91 ds-tat, FAM labeled, is commonly used in studies of oxidative stress, redox signaling, enzyme assembly dynamics, inflammation, kidney disease, vascular dysfunction, and cardiovascular pathology involving NADPH oxidase activity.