IGRP Catalytic Subunit-related Protein (206-214)

Product Name: IGRP Catalytic Subunit-related Protein (206-214)

Sequence One Letter Code: VYLKTNVFL

Sequence Three Letter Code: H-Val-Tyr-Leu-Lys-Thr-Asn-Val-Phe-Leu-OH

Chemical Formula:C54H85N11O13

Molecular Weight: 1096.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: mouse

Conjugation: Unconjugated

Code Nacres: NA.26

Application: IGRP (206–214) is a synthetic peptide corresponding to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit-related protein, a major autoantigen in type 1 diabetes. This peptide is recognized by autoreactive T cells specific for IGRP and proinsulin and has been shown to induce diabetes in non-obese diabetic mice. IGRP (206–214) is widely used in immunology and diabetes research to study antigen-specific T-cell responses, pancreatic β-cell destruction, autoimmune mechanisms, immune tolerance, and development of immune-modulating therapeutic strategies targeting type 1 diabetes.