IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Product Name: IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Sequence One Letter Code: SGIPYIISYLHPGNTILHVD

Sequence Three Letter Code: H-Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp-OH

Chemical Formula:C103H157N25O29

Molecular Weight: 2209.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human, macaque

Conjugation: Unconjugated

Code Nacres: NA.26

Application: IRBP (161–180) is a synthetic peptide corresponding to amino acids 161–180 of interphotoreceptor retinoid-binding protein, located within its first homologous repeat. This sequence is a major pathogenic T-cell epitope capable of inducing experimental autoimmune uveitis, a model of human posterior uveitis. IRBP (161–180) is widely used in ocular immunology research to study autoimmune mechanisms affecting the eye, retinal inflammation, T-cell-mediated immune responses, and immune privilege. This peptide supports investigations of uveitis pathogenesis, antigen-specific inflammation, retinal autoimmunity, and immunomodulatory therapeutic strategies.