LVTX-8

LVTX-8 is an amphipathic α-helical cell-penetrating peptide derived from the venom of the spider Lycosa vittata. It exhibits significant anticancer activity, especially against lung cancer cells, by inducing apoptosis and suppressing cell proliferation and migration. Transcriptomic studies suggest that LVTX-8 modulates invasion- and proliferation-related pathways through p53-associated signaling mechanisms. This peptide is widely used in cancer biology research to explore venom-derived anticancer peptides, apoptosis induction, tumor migration inhibition, cell-penetrating peptide activity, and therapeutic strategies targeting cancer cell survival, proliferation, and invasive behavior.

Product Name: LVTX-8

Sequence One Letter Code: IWLTALKFLGKNLGKHLAKQQLSKL

Sequence Three Letter Code: H-Ile-Trp-Leu-Thr-Ala-Leu-Lys-Phe-Leu-Gly-Lys-Asn-Leu-Gly-Lys-His-Leu-Ala-Lys-Gln-Gln-Leu-Ser-Lys-Leu-OH

Chemical Formula:C135H226N36O31

Molecular Weight: 2847.72

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Spider

Conjugation: Unconjugated