[Lys0]-Bradykinin (Kallidin)

Product Name: [Lys0]-Bradykinin (Kallidin)

Sequence One Letter Code: KRPPGFSPFR

Sequence Three Letter Code: H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH

Cas No: 342-10-9

Chemical Formula:C56H85N17O12

Molecular Weight: 1188.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

IUPAC: (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

INCHIKEY: FYSKZKQBTVLYEQ-FSLKYBNLSA-N

INCHI:

InChI=1S/C56H85N17O12/c57-24-8-7-18-36(58)46(76)67-37(19-9-25-63-55(59)60)51(81)73-29-13-23-44(73)53(83)72-28-11-21-42(72)49(79)65-32-45(75)66-39(30-34-14-3-1-4-15-34)47(77)70-41(33-74)52(82)71-27-12-22-43(71)50(80)69-40(31-35-16-5-2-6-17-35)48(78)68-38(54(84)85)20-10-26-64-56(61)62/h1-6,14-17,36-44,74H,7-13,18-33,57-58H2,(H,65,79)(H,66,75)(H,67,76)(H,68,78)(H,69,80)(H,70,77)(H,84,85)(H4,59,60,63)(H4,61,62,64)/t36-,37-,38-,39-,40-,41-,42-,43-,44-/m0/s1

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: [Lys0]-Bradykinin, also known as kallidin, is a decapeptide kinin closely related to bradykinin and functions as a potent inflammatory mediator. Kinins are generated during acute and chronic inflammatory responses and act mainly through B1 and B2 receptors. [Lys0]-Bradykinin is involved in vasodilation, pain signaling, vascular permeability, immune activation, and inflammatory tissue responses. Elevated levels of bradykinin and kallidin have been detected in tear fluid from ocular allergic patients, supporting its relevance in eye inflammation research. This peptide is widely used in kinin receptor pharmacology and inflammatory disease studies.