[Lys(Ac)14/18/23]-Histone H3 (1-24)-GGK(Biotin)

Product Name: [Lys(Ac)14/18/23]-Histone H3 (1-24)-GGK(Biotin)

Sequence One Letter Code: ARTKQTARKSTGG-K(Ac)-APR-K(Ac)-QLAT-K(Ac)-A-GGK(Biotin)

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys(Ac)-Ala-Pro-Arg-Lys(Ac)-Gln-Leu-Ala-Thr-Lys(Ac)-Ala-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 3149.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: Histone H3 (1–24), K14ac/K18ac/K23ac-GGK(Biotin) is a synthetic histone H3 peptide hyperacetylated at lysines 14, 18, and 23, a modification pattern associated with transcriptional activation and open chromatin states. Multi-site acetylation promotes chromatin relaxation and enhances recruitment of transcriptional machinery and acetyl-lysine reader proteins. The peptide includes a C-terminal GG linker followed by biotinylated lysine for affinity capture, pull-down, and binding assays. This hyperacetylated histone peptide is widely used in chromatin biology and epigenetics research to study acetylation-dependent protein interactions, transcriptional regulation, and gene expression mechanisms.