[Lys(Ac)8]-Histone H4 (1-20)

Product Name: [Lys(Ac)8]-Histone H4 (1-20)

Sequence One Letter Code: SGRGKGG-K(Ac)-GLGKGGAKRHRK

Sequence Three Letter Code: H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys(Ac)-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-OH

Molecular Weight: 2034.5

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: [Lys(Ac)8]-Histone H4 (1–20) is a synthetic N-terminal histone H4 peptide acetylated at lysine 8, an epigenetic modification associated with chromatin regulation and transcriptional control. H4K8 acetylation has been reported as a potential prognostic marker in resected non-small-cell lung cancer and may also participate in somatic hypermutation by facilitating recruitment of error-prone DNA polymerases during DNA repair. This modified histone peptide is commonly used in epigenetics, chromatin biology, cancer research, histone acetylation studies, transcription regulation assays, and investigations of modification-dependent protein recognition.