[Lys(Me1)4]-Histone H3 (1–10) is a synthetic histone H3 peptide corresponding to residues 1–10 and monomethylated at lysine 4. H3K4 monomethylation is an epigenetic modification associated with transcriptional regulation, enhancer activity, and chromatin priming. It is often enriched at enhancer regions and can serve as a precursor to higher methylation states. This modified histone peptide is commonly used to investigate histone methylation dynamics, methyltransferase and demethylase specificity, methyl-lysine reader protein binding, chromatin accessibility, enhancer-associated regulatory mechanisms, and gene expression control in epigenetics research.
Product Name: [Lys(Me1)4]-Histone H3 (1-10)
Sequence One Letter Code: ART-K(Me1)-QTARKS
Sequence Three Letter Code: H-Ala-Arg-Thr-Lys(Me1)-Gln-Thr-Ala-Arg-Lys-Ser-OH
Molecular Weight: 1160.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Unconjugated
Code Nacres: NA.26
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