[Lys(Me2)9]-Histone H3 (3-17)

Product Name: [Lys(Me2)9]-Histone H3 (3-17)

Sequence One Letter Code: TKQTAR-K(Me2)-STGGKAPR

Sequence Three Letter Code: H-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me2)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-OH

Molecular Weight: 1615

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

 Code Nacres: NA.26

Application: [Lys(Me2)9]-Histone H3 (3–17) is a synthetic histone H3 peptide corresponding to residues 3–17 and dimethylated at lysine 9. H3K9 dimethylation is associated with facultative heterochromatin, transcriptional repression, and chromatin compaction. It also serves as a regulatory intermediate between mono- and trimethylated H3K9 states. This modified peptide is widely used to study histone methylation dynamics, lysine methyltransferase and demethylase specificity, protein recognition of repressive chromatin marks, methyl-lysine reader domains, chromatin regulation, and epigenetic mechanisms controlling gene expression.