MHC II Ea chain (Ea) (52–68) peptide (AbßEp)

Product Name: MHC II Ea chain (Ea) (52–68) peptide (AbßEp)

Sequence One Letter Code: ASFEAQGALANIAVDKA

Sequence Three Letter Code: H-Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH

Chemical Formula:C73H118N20O25

Molecular Weight: 1675.9

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human, mouse, rat, macaque

Conjugation: Unconjugated

Code Nacres: NA.26

Application: MHC II Eα chain (52–68), also known as AbβEp, is a well-characterized class II MHC-derived epitope from the Eα chain. This peptide naturally occupies a substantial proportion of I-Aᵇ-bound peptides, making it a key model antigen for studying MHC II antigen presentation. It is commonly used in immunology research to investigate CD4⁺ T-cell activation, peptide loading, antigen-processing pathways, adaptive immune recognition, and immune tolerance. MHC II Eα chain (52–68) is a valuable reagent for experiments focused on MHC class II biology and T-cell-mediated immune responses.