Noxa A BH3 peptide, cell permeable

Product Name: Noxa A BH3 peptide, cell permeable

Sequence One Letter Code: rrrrrrrrGAELPPEFAAQLRKIGDKVYC

Sequence Three Letter Code: H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-Ala-Glu-Leu-Pro-Pro-Glu-Phe-Ala-Ala-Gln-Leu-Arg-Lys-Ile-Gly-Asp-Lys-Val-Tyr-Cys-OH

Chemical Formula:C152H261N59O38S1

Molecular Weight: 3555.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Synthetic construct

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Noxa A BH3 Cell-Permeable Peptide is derived from the BH3 domain of Noxa A, covering amino acid residues 17–36. Noxa A is a pro-apoptotic BH3-only protein that selectively antagonizes anti-apoptotic BCL-2 family members. This peptide is engineered with a poly-D-arginine sequence and glycine linker to enhance cellular uptake, making it useful for cell-based apoptosis studies. Noxa A BH3 Cell-Permeable Peptide is widely used to investigate mitochondrial death pathways, BCL-2 family protein interactions, apoptotic resistance mechanisms, BH3 mimetic activity, and cancer-related cell death signaling.