OVA-A2 Peptide, SAINFEKL, OVA (257-264) Variant

Product Name: OVA-A2 Peptide, SAINFEKL, OVA (257-264) Variant

Sequence One Letter Code: SAINFEKL

Sequence Three Letter Code: H-Ser-Ala-Ile-Asn-Phe-Glu-Lys-Leu-OH

Chemical Formula:C42H68N10O13

Molecular Weight: 921.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: chicken

Conjugation: Unconjugated

Code Nacres: NA.26

Application: OVA-A2 (SAINFEKL) is an altered peptide ligand derived from the immunodominant ovalbumin epitope SIINFEKL. Presented by the murine H-2Kᵇ class I MHC molecule, this variant introduces a substitution that modulates T-cell receptor signaling while maintaining MHC binding. OVA-A2 is frequently used to study graded T-cell responses, antigen potency, T-cell activation thresholds, and the relationship between peptide structure and immune signaling. This peptide is valuable for research on CD8⁺ T-cell tolerance, anergy, functional plasticity, altered peptide ligands, and antigen-specific immune modulation.