Plasminogen Activator Acrosine Substrate, fluorescent Z-Gly-Gly-Arg-AFC

Product Name: Plasminogen Activator Acrosine Substrate, fluorescent Z-Gly-Gly-Arg-AFC

Sequence One Letter Code: Z-GGR-AFC

Sequence Three Letter Code: Z-Gly-Gly-Arg-AFC

Chemical Formula:C28H30F3N7O7

Molecular Weight: 633.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Source / Species: Synthetic construct

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26

Application: Z-Gly-Gly-Arg-AFC is a fluorogenic peptide substrate designed for measuring plasminogen activators and acrosin-like protease activity. Upon enzymatic cleavage, the AFC fluorophore is released, generating a strong fluorescence signal measurable at Abs/Em 380/500 nm. This substrate enables sensitive, quantitative monitoring of serine protease activity in biochemical assay systems. Z-Gly-Gly-Arg-AFC is widely used in protease kinetics, fibrinolysis pathway studies, reproductive biology research involving acrosin, and screening of protease inhibitors. It provides a reliable tool for enzymology, assay development, and mechanistic studies of protease-mediated biological processes.