SV40 Large T-antigen Nuclear Localization Signal (NLS) derived peptide

Product Name: SV40 Large T-antigen Nuclear Localization Signal (NLS) derived peptide

Sequence One Letter Code: CGGGPKKKRKVED

Sequence Three Letter Code: H-Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp-OH

Chemical Formula:C58H104N20O18S

Molecular Weight: 1401.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Polyoma virus

Conjugation: Unconjugated

Code Nacres: NA.26

Application: SV40 Large T-Antigen NLS Peptide corresponds to residues 47–55 of SV40 large T-antigen and contains the classical nuclear localization signal sequence PKKKRKV. This NLS motif is one of the most widely used sequences for mediating active nuclear import through the importin-dependent transport pathway. The peptide is commonly conjugated to proteins, peptides, nucleic acid carriers, or nanoparticles to facilitate nuclear targeting. SV40 Large T-Antigen NLS Peptide is widely used in cell biology, gene delivery, intracellular trafficking, nucleocytoplasmic transport research, and development of nuclear-targeted molecular delivery systems.